Frusemide for cardiac failure in infancy.

Frusemide in heart failure of infancy.

Vitamin D deficiency and cardiac failure in infancy.

A girl aged 412 months was referred in shock with acute heart failure and respiratory distress. She was of West African descent but had been born in the UK and breastfed from birth. Echocardiogram revealed a poorly functioning dilated heart (fractional shortening 6.5%; Table 1). She was admitted to the paediatric intensive-care unit where treatment included inotropic agents, furosemide and capt...

Antagonistic effect of non-steroidal anti-inflammatory drugs on frusemide-induced diuresis in cardiac failure.

Antagonistic effect of non-steroidal anti-inflammatory drugs on frusemide-induced diuresis in cardiac failure A C YEUNG LAIWAH, R A MACTIER Non-steroidal anti-inflammatory drugs (NSAID) with prosta-glandin synthetase inhibitory activity are widely used to treat patients with arthritis. The diuretic effect of frusemide is thought to be mediated at least in part by renal prostaglandins.1 The anta...

Enalapril for severe heart failure in infancy.

Eight infants aged between 4 days and 12 weeks with severe heart failure that was refractory to optimal conventional treatment with diuretics were treated with enalapril. The starting dose was 0.1 mg/kg/day, increasing according to response to 0.12-0.43 mg/kg/day. One infant with severe myocarditis did not tolerate enalapril because of hypotension and later died of intractable heart failure. Si...

Cardiac surgery in early infancy.

IMPORTANT advances have been made in the diagnosis and treatment of congenital heart disease (CHD) in early infancy. Accurate diagnosis is now possible in the first days or even hours of life. Operation is also possible at this early age and very often it provides the only chance for survival. The risk of conservative treatment often exceeds the risk of the operation. An aggressive approach to ...